How often should epinephrine be given during pediatric CPR?

How often should epinephrine be given during pediatric CPR?

• A. Every 3–5 minutes
• B. Every 1 minute
• C. Every 8–10 minutes
• D. Every 15 minutes

Answer: (A)

During pediatric CPR, epinephrine is given every 3-5 minutes. This timing aligns with the CPR cycle and helps boost coronary and cerebral perfusion pressures by causing vasoconstriction during chest compressions, increasing the chance of return of spontaneous circulation. Giving it more often doesn’t add benefit and can raise afterload or cause excessive vasoconstriction, while waiting longer than about 5 minutes reduces perfusion during CPR. The usual dose is 0.01 mg/kg of 1:10,000 IV/IO per dose, repeated every 3-5 minutes until ROSC.

During pediatric CPR, epinephrine is given every 3-5 minutes. This timing aligns with the CPR cycle and helps boost coronary and cerebral perfusion pressures by causing vasoconstriction during chest compressions, increasing the chance of return of spontaneous circulation. Giving it more often doesn’t add benefit and can raise afterload or cause excessive vasoconstriction, while waiting longer than about 5 minutes reduces perfusion during CPR. The usual dose is 0.01 mg/kg of 1:10,000 IV/IO per dose, repeated every 3-5 minutes until ROSC.